| Date | Location | Result | |
| Nov 11, 2000 | Marshall, TX | Mary Hardin-Baylor 52, East Texas Baptist 7 | Box score |
| Nov 11, 2000 | Alpine, TX | Austin College 28, Sul Ross State 27 | Box score |
| Nov 11, 2000 | Clinton, MS | Mississippi College 35, Louisiana College 21 | Box score |
| Nov 11, 2000 | Brownwood, Texas | Howard Payne 45, Texas Lutheran 13 | Box score |
| Nov 11, 2000 | Shelton Stadium | Hardin-Simmons 13, McMurry 3 | Box score |
| Nov 04, 2000 | Abilene, Tx | McMurry 56, Sul Ross State 28 | Box score |
| Nov 04, 2000 | Pineville,La. | Louisiana College 31, East Texas Baptist 14 | Box score |
| Nov 04, 2000 | Seguin, Texas | Texas Lutheran 34, Mississippi College 32 | Box score |
| Nov 04, 2000 | Belton, Texas | Hardin-Simmons 21, Mary Hardin-Baylor 7 | Box score |
| Nov 04, 2000 | Sherman, TX | Howard Payne 17, Austin College 0 | Box score |
| OCT 27, 2000 | Alpine, TX | Mary Hardin-Baylor 52, Sul Ross State 14 | Box score |
| Oct 28, 2000 | Marshall, Tx | Hardin-Simmons 44, East Texas Baptist 7 | Box score |
| Oct 28, 2000 | Clinton, Miss. | Austin College 33, Mississippi College 30 | Box score |
| Oct 28, 2000 | Brownwood, Texas | McMurry 34, Howard Payne 26 | Box score |
| Oct 28, 2000 | Pineville,La. | Texas Lutheran 45, Louisiana College 28 | Box score |
| Oct 21, 2000 | Seguin, Texas | Texas Lutheran 35, East Texas Baptist 7 | Box score |
| Oct 21, 2000 | Belton, Texas | Mary Hardin-Baylor 19, Howard Payne 14 | Box score |
| Oct 21, 2000 | Abilene, Tx | McMurry 34, Mississippi College 21 | Box score |
| Oct 21, 2000 | Abilene, Texas | Hardin-Simmons 42, Sul Ross State 6 | Box score |
| Oct 21, 2000 | Sherman, Texas | Austin College 21, Louisiana College 3 | Box score |
| Oct. 14 | Marshall, Texas | Sul Ross State 40, East Texas Baptist 21 | Box score |
| Oct 14, 2000 | Clinton, MS | Mary Hardin-Baylor 24, Mississippi College 6 | Box score |
| Oct 14, 2000 | Pineville,La. | McMurry 26, Louisiana College 0 | Box score |
| Oct 14, 2000 | Seguin, Texas | Austin College 35, Texas Lutheran 14 | Box score |
| Oct 14, 2000 | Brownwood | Hardin-Simmons 10, Howard Payne 9 | Box score |
| Oct 7, 2000 | Alpine, TX | Howard Payne 27, Sul Ross State 7 | Box score |
| Oct. 7, 2000 | Marshall, TX | Austin College 34, East Texas Baptist 28 | Box score |
| Oct 07, 2000 | Abilene, Tx | McMurry 51, Texas Lutheran 10 | Box score |
| Oct 07, 2000 | Belton, Texas | Mary Hardin-Baylor 38, Louisiana College 16 | Box score |
| Oct 07, 2000 | Abilene, Texas | Hardin-Simmons 35, Mississippi College 21 | Box score |
| Sep 30, 2000 | Seguin, Texas | Mary Hardin-Baylor 42, Texas Lutheran 28 | Box score |
| Sep 30, 2000 | Clinton, MS | Mississippi College 34, Sul Ross State 7 | Box score |
| Sep 30, 2000 | Brownwood | Howard Payne 35, East Texas Baptist 0 | Box score |
| Sep 30, 2000 | Pineville,La. | Hardin-Simmons 45, Louisiana College 12 | Box score |
| Sep 30, 2000 | Sherman, TX | Austin College 24, McMurry 21 | Box score |
| Sept. 23 | Alpine, Texas | Sul Ross State 42, Louisiana College 11 | Box score |
| Sep 23, 2000 | Marshall, TX | East Texas Baptist 28, McMurry 14 | Box score |
| Sep 23, 2000 | Belton, Texas | Mary Hardin-Baylor 27, Austin College 0 | Box score |
| Sep 23, 2000 | Brownwood | Howard Payne 35, Mississippi College 25 | Box score |
| Sep 23, 2000 | Abilene, Texas | Hardin-Simmons 42, Texas Lutheran 14 | Box score |
| Sep 16, 2000 | Alpine, Texas | Texas Lutheran 23, Sul Ross State 21 | Box score |
| Sep 16, 2000 | Abilene, Texas | Mary Hardin-Baylor 20, McMurry 6 | Box score |
| Sep 16, 2000 | Clinton, MS | Mississippi College 50, East Texas Baptist 6 | Box score |
| Sep 16, 2000 | Pineville | Howard Payne 36, Louisiana College 14 | Box score |
| Sep 16,2000 | Sherman, Texas | Hardin-Simmons 27, Austin College 14 | Box score |
| Sept 9, 2000 | Waxahachie, TX | East Texas Baptist 42, Southwest Assemblies 6 | Box score |
| Sep 09, 2000 | Belton, Texas | Mary Hardin-Baylor 34, Bellhaven College 17 | Box score |
| Sep 09, 2000 | Sherman, Texas | Austin College 31, Millsaps College 23 | Box score |
| Sep 09, 2000 | Abilene, Texas | Hardin-Simmons 37, Wisconsin-Whitewater 8 | Box score |
| Sep 09, 2000 | Abilene, TX | McMurry 35, William Jewell Coll. 14 | Box score |
| Sep 02, 2000 | Jackson, MS | Millsaps College 20, Mississippi College 19 | Box score |
| Sep 02, 2000 | Seguin, Texas | Trinity (Texas) 40, Texas Lutheran 21 | Box score |
| Sep 02, 2000 | Pineville,LA | Louisiana College 60, Southwest Assemblies 0 | Box score |
| Sep 2, 2000 | Wisconsin-Whitewater | Wisconsin-Whitewater 28, Howard Payne 14 | Box score |